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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Ethanol use and sleep ： ウィキペディア英語版 Ethanol use and sleep Ethanol, the type of alcohol found in alcoholic beverages, can exacerbate sleep problems. During abstinence, sleep disruption is one of the greatest predictors of relapse.〔Feige, B., Scaal, S., Hornyak, M., Gann, H., Riemann, D. Sleep electroencephalographic spectral power after withdrawal from alcohol in alcohol-dependent patients. ALcoholism: Clinical and Experimental Research. 2007 Jan; 31 (1): 19-27.〕 ==Moderate alcohol consumption and sleep disruptions== Moderate alcohol consumption 30–60 minutes before bedtime results in disruptions in sleep maintenance and sleep architecture that are mediated by blood alcohol levels.〔Roehrs, T., and Roth, T. Sleep, sleepiness, and alcohol use. Alcohol Research & Health. 2001; 25(2):101-109.〕 Disruptions in sleep maintenance are most marked once alcohol has been completely metabolized from the body. Under conditions of moderate alcohol consumption where blood alcohol levels average 0.06–0.08% and decrease 0.01–0.02% per hour, an alcohol clearance rate of 4–5 hours would coincide with disruptions in sleep maintenance in the second half of an 8-hour sleep episode.〔 In terms of sleep architecture, moderate doses of alcohol facilitate "rebounds" in rapid eye movement (REM) and stage 1 sleep; following suppression in REM and stage 1 sleep in the first half of an 8-hour sleep episode, REM and stage 1 sleep increase well beyond baseline in the second half. Moderate doses of alcohol also increase slow wave sleep (SWS) in the first half of an 8-hour sleep episode.〔 Enhancements in REM sleep and SWS following moderate alcohol consumption are mediated by reductions in glutamatergic activity by adenosine in the central nervous system.〔 In addition, tolerance to changes in sleep maintenance and sleep architecture develops within 3 days of alcohol consumption before bedtime.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ethanol use and sleep」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.